NP-MRD: Showing NP-Card for (+)-Gnetuhainin A (NP0081079)

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Record Information

Version

1.0

Created at

2022-04-29 02:03:31 UTC

Updated at

2022-04-29 02:03:31 UTC

NP-MRD ID

NP0081079

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(+)-Gnetuhainin A

Description

4-[(2R,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol belongs to the class of organic compounds known as 2-arylbenzofuran flavonoids. These are phenylpropanoids containing the 2-phenylbenzofuran moiety. (+)-Gnetuhainin A is found in Gnetum hainanense. It was first documented in 2022 (PMID: 35490355). Based on a literature review a significant number of articles have been published on 4-[(2R,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol (PMID: 35490354) (PMID: 35490353) (PMID: 35490352) (PMID: 35490351).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652304292204032D          

 35 39  0  0  1  0            999 V2000
    3.3523    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    3.1729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    4.4104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    4.8229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    5.6479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    6.0604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    5.6479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    4.8229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    6.8854    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387    2.1904    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6538    1.5229    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.1387    0.8555    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    2.2374    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    2.2374    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    0.8085    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    0.8085    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    0.0940    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6462    1.5229    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8838    2.9750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0768    3.1465    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1781    3.9312    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3739    4.5442    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1809    4.3727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4358    3.5881    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7329    4.9858    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9851    4.1027    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    0.6979    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  1  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
  9 14  1  0  0  0  0
 12 15  1  0  0  0  0
  5 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
  4 18  1  0  0  0  0
 17 19  1  1  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
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 24 25  1  0  0  0  0
 22 26  1  0  0  0  0
 16 27  1  1  0  0  0
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 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 30 31  1  0  0  0  0
 31 32  2  0  0  0  0
 27 32  1  0  0  0  0
 31 33  1  0  0  0  0
 29 34  1  0  0  0  0
  2 35  1  0  0  0  0
M  END

     RDKit          3D

 57 61  0  0  0  0  0  0  0  0999 V2000
    6.5042   -0.6594   -3.5660 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6276   -0.4339   -2.5044 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9694    0.1967   -1.3395 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0200    0.3701   -0.3455 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7109   -0.0681   -0.4634 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7863    0.1678    0.6471 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5298   -0.2086    0.6451 C   0  0  0  0  0  0  0  0  0  0  0  0
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    1.0613    0.7300    2.9030 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2010    0.9876    3.9841 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6558    1.6700    5.0889 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0957    0.5426    3.9073 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5167   -0.1339    2.7930 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6481   -0.3914    1.7084 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4782   -1.1380    0.7889 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.0986   -1.5387   -0.5191 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2362   -0.7887   -1.6921 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8691   -1.2570   -2.9374 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0136   -0.4953   -4.0916 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3400   -2.5132   -3.0763 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1796   -3.3007   -1.9585 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3670   -4.5928   -2.1181 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5481   -2.8156   -0.7486 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8518   -0.5905    1.0226 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.1366    0.7993    0.7690 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2852    1.8259    0.4834 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6394    3.1359    0.2758 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9778    3.4505    0.3620 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3863    4.7691    0.1588 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9043    2.4617    0.6482 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4964    1.1730    0.8460 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4410    0.2074    1.1296 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7906   -0.6774    2.4950 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3768   -0.6950   -1.6247 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3386   -0.8718   -2.6345 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0493   -1.5317   -3.5842 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9918    0.5453   -1.2323 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3579    0.8762    0.5473 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1819    0.6804    1.5044 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1839   -0.7197   -0.2497 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0797    1.0842    2.9720 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6056    2.0018    5.1562 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7591    0.7406    4.7392 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5783   -2.1667    1.3863 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6410    0.1864   -1.6474 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2653    0.1280   -4.4275 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0421   -2.9061   -4.0500 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4915   -5.1837   -1.3088 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4038   -3.4735    0.1243 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6558   -1.2956    0.7541 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375    1.6007    0.4020 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8881    3.8749    0.0558 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4283    5.3831    0.9821 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9397    2.7643    0.7039 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4082    0.4707    1.1840 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3830   -1.0561   -1.7769 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0407   -1.3759   -3.5496 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  3  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  2  0
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  8 14  2  0
 14 15  1  0
 15 24  1  0
 24 33  1  0
 33 13  1  0
 13 12  2  0
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 10  9  2  0
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 18 19  1  0
 18 20  2  0
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  5 34  1  0
 34 35  2  0
 35  2  1  0
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 31 25  1  0
 23 16  1  0
 13 14  1  0
  1 36  1  0
  3 37  1  0
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 15 44  1  1
 24 50  1  6
 12 43  1  0
 11 42  1  0
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 26 51  1  0
 27 52  1  0
 29 53  1  0
 30 54  1  0
 32 55  1  0
 17 45  1  0
 19 46  1  0
 20 47  1  0
 22 48  1  0
 23 49  1  0
 34 56  1  0
 35 57  1  0
M  END


  Mrv1652304292204032D          

 35 39  0  0  1  0            999 V2000
    3.3523    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    3.1729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    4.4104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    4.8229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    5.6479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    6.0604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    5.6479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    4.8229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    6.8854    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387    2.1904    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6538    1.5229    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.1387    0.8555    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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   -1.4087    2.2374    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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   -0.5837    0.8085    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    0.0940    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    0.8838    2.9750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0768    3.1465    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1781    3.9312    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3739    4.5442    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1809    4.3727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4358    3.5881    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7329    4.9858    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9851    4.1027    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    0.6979    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  1  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
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 12 15  1  0  0  0  0
  5 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
  4 18  1  0  0  0  0
 17 19  1  1  0  0  0
 19 20  2  0  0  0  0
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 19 24  1  0  0  0  0
 24 25  1  0  0  0  0
 22 26  1  0  0  0  0
 16 27  1  1  0  0  0
 27 28  2  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 30 31  1  0  0  0  0
 31 32  2  0  0  0  0
 27 32  1  0  0  0  0
 31 33  1  0  0  0  0
 29 34  1  0  0  0  0
  2 35  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0081079

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC1=CC=C(\C=C\C2=C3[C@@H]([C@@H](OC3=CC(O)=C2)C2=CC=C(O)C=C2O)C2=CC(O)=CC(O)=C2)C=C1

> <INCHI_IDENTIFIER>
InChI=1S/C28H22O7/c29-18-5-2-15(3-6-18)1-4-16-9-22(33)14-25-26(16)27(17-10-20(31)12-21(32)11-17)28(35-25)23-8-7-19(30)13-24(23)34/h1-14,27-34H/b4-1+/t27-,28-/m0/s1

> <INCHI_KEY>
KYXFGKLZVUDIIX-PAKBJIOWSA-N

> <FORMULA>
C28H22O7

> <MOLECULAR_WEIGHT>
470.477

> <EXACT_MASS>
470.136553048

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
57

> <JCHEM_AVERAGE_POLARIZABILITY>
47.96610166081747

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
4-[(2R,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol

> <ALOGPS_LOGP>
4.09

> <JCHEM_LOGP>
5.656929148333334

> <ALOGPS_LOGS>
-5.03

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.841765628279365

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.41297507395554

> <JCHEM_PKA_STRONGEST_BASIC>
-4.906433147763327

> <JCHEM_POLAR_SURFACE_AREA>
130.61

> <JCHEM_REFRACTIVITY>
132.02040000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
4.41e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
4-[(2R,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 29-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   29-APR-22         0                                  
HETATM    1  C   UNK     0       6.258   3.613   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       6.258   2.073   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       4.924   1.303   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       3.590   2.073   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       3.590   3.613   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       4.924   4.383   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.924   5.923   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       6.258   6.693   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       6.258   8.233   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.924   9.003   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.924  10.543   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       6.258  11.313   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       7.591  10.543   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       7.591   9.003   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       6.258  12.853   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       2.126   4.089   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       1.220   2.843   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       2.126   1.597   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0      -0.320   2.843   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -1.090   4.177   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -2.630   4.177   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -3.400   2.843   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -2.630   1.509   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -1.090   1.509   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      -0.320   0.175   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0      -4.940   2.843   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       1.650   5.553   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       0.143   5.874   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -0.333   7.338   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       0.698   8.483   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       2.204   8.162   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       2.680   6.698   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       3.235   9.307   0.000  0.00  0.00           O+0
HETATM   34  O   UNK     0      -1.839   7.658   0.000  0.00  0.00           O+0
HETATM   35  O   UNK     0       7.591   1.303   0.000  0.00  0.00           O+0
CONECT    1    2    6                                                       
CONECT    2    1    3   35                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5   18                                                  
CONECT    5    4    6   16                                                  
CONECT    6    5    1    7                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   14                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   15                                                  
CONECT   13   12   14                                                       
CONECT   14   13    9                                                       
CONECT   15   12                                                            
CONECT   16    5   17   27                                                  
CONECT   17   16   18   19                                                  
CONECT   18   17    4                                                       
CONECT   19   17   20   24                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23   26                                                  
CONECT   23   22   24                                                       
CONECT   24   23   19   25                                                  
CONECT   25   24                                                            
CONECT   26   22                                                            
CONECT   27   16   28   32                                                  
CONECT   28   27   29                                                       
CONECT   29   28   30   34                                                  
CONECT   30   29   31                                                       
CONECT   31   30   32   33                                                  
CONECT   32   31   27                                                       
CONECT   33   31                                                            
CONECT   34   29                                                            
CONECT   35    2                                                            
MASTER        0    0    0    0    0    0    0    0   35    0   78    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₈H₂₂O₇

Average Mass

470.4770 Da

Monoisotopic Mass

470.13655 Da

IUPAC Name

4-[(2R,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol

Traditional Name

4-[(2R,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol

CAS Registry Number

Not Available

SMILES

OC1=CC=C(\C=C\C2=C3[C@@H]([C@@H](OC3=CC(O)=C2)C2=CC=C(O)C=C2O)C2=CC(O)=CC(O)=C2)C=C1

InChI Identifier

InChI=1S/C28H22O7/c29-18-5-2-15(3-6-18)1-4-16-9-22(33)14-25-26(16)27(17-10-20(31)12-21(32)11-17)28(35-25)23-8-7-19(30)13-24(23)34/h1-14,27-34H/b4-1+/t27-,28-/m0/s1

InChI Key

KYXFGKLZVUDIIX-PAKBJIOWSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Gnetum hainanense	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 2-arylbenzofuran flavonoids. These are phenylpropanoids containing the 2-phenylbenzofuran moiety.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

2-arylbenzofuran flavonoids

Sub Class

Not Available

Direct Parent

2-arylbenzofuran flavonoids

Alternative Parents

Substituents

2-arylbenzofuran flavonoid
1-phenylcoumaran
Stilbene
Coumaran
Styrene
Resorcinol
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Phenol
Alkyl aryl ether
Benzenoid
Monocyclic benzene moiety
Oxacycle
Organoheterocyclic compound
Ether
Organic oxygen compound
Hydrocarbon derivative
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4.09	ALOGPS
logP	5.66	ChemAxon
logS	-5	ALOGPS
pKa (Strongest Acidic)	8.41	ChemAxon
pKa (Strongest Basic)	-4.9	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	130.61 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	132.02 m³·mol⁻¹	ChemAxon
Polarizability	47.97 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163011402

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Baumbusch J, Blakey EP, Carapellotti AM, Dohmen M, Fick DM, Kagan SH, Melendez-Torres GJ, Morgan BE, Munsterman E, Resnick B, Young HM: Nurses and the decade of healthy ageing: An unprecedented opportunity. Int J Older People Nurs. 2022 May;17(3):e12469. doi: 10.1111/opn.12469. [PubMed:35490355 ]
Hill NL, Bratlee-Whitaker E, Wion RK, Madrigal C, Bhargava S, Mogle J: Factors that influence the emotional impact of memory problems in older adults: A qualitative descriptive study. Int J Older People Nurs. 2022 May;17(3):e12439. doi: 10.1111/opn.12439. Epub 2021 Dec 8. [PubMed:35490354 ]
Polastri M, Loforte A, Swol J: "Racing team" or "orchestra" approach? Two different perspectives on providing care in emergency and critical settings. Artif Organs. 2022 May 1. doi: 10.1111/aor.14274. [PubMed:35490353 ]
Wei YF, Wang L, Xia ZY, Gou M, Sun ZY, Lv WF, Tang YQ: Microbial communities in crude oil phase and filter-graded aqueous phase from a Daqing oilfield after polymer flooding. J Appl Microbiol. 2022 May 1. doi: 10.1111/jam.15603. [PubMed:35490352 ]
Authors unspecified: CORRIGENDUM. Transbound Emerg Dis. 2022 May 1. doi: 10.1111/tbed.14572. [PubMed:35490351 ]

Showing NP-Card for (+)-Gnetuhainin A (NP0081079)

MOL for NP0081079 ((+)-Gnetuhainin A)

3D MOL for NP0081079 ((+)-Gnetuhainin A)

3D SDF for NP0081079 ((+)-Gnetuhainin A)

3D-SDF for NP0081079 ((+)-Gnetuhainin A)

PDB for NP0081079 ((+)-Gnetuhainin A)

3D PDB for NP0081079 ((+)-Gnetuhainin A)

SMILES for NP0081079 ((+)-Gnetuhainin A)

INCHI for NP0081079 ((+)-Gnetuhainin A)

Structure for NP0081079 ((+)-Gnetuhainin A)

3D Structure for NP0081079 ((+)-Gnetuhainin A)