NP-MRD: Showing NP-Card for (+)-Haiderine (NP0068031)

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Record Information

Version

1.0

Created at

2022-04-28 12:55:10 UTC

Updated at

2022-04-28 12:55:10 UTC

NP-MRD ID

NP0068031

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(+)-Haiderine

Description

Methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0²,⁷.0¹²,¹⁷]Heptadeca-2,4,6,12-tetraene-17-carboxylate belongs to the class of organic compounds known as tetrahydroisoquinolines. These are tetrahydrogenated isoquinoline derivatives. (+)-Haiderine is found in Cocculus hirsutus (L.) Diels . It was first documented in 2022 (PMID: 35487686). Based on a literature review a significant number of articles have been published on methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0²,⁷.0¹²,¹⁷]Heptadeca-2,4,6,12-tetraene-17-carboxylate (PMID: 35487685) (PMID: 35487684) (PMID: 35487683) (PMID: 35487682).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 44 47  0  0  0  0  0  0  0  0999 V2000
    3.2443   -1.3220    2.3985 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7075   -0.4594    1.4116 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3608   -0.4743    1.0480 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6129   -1.2796    1.6188 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9511    0.4963   -0.0090 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.2728    1.8530    0.4108 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6998    2.8390   -0.6384 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0191    2.3144   -1.1994 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7361    0.9319   -1.7100 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8372    0.1574   -1.1851 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3612   -1.2104   -1.5193 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0236   -1.1943   -1.1389 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9423   -1.6748   -2.1003 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3272   -1.0951   -1.9559 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5707   -0.6858   -0.5511 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7681   -0.9459    0.0345 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0252   -0.5720    1.3307 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2260   -0.8212    1.9498 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0097    0.0848    2.0222 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2720    0.4628    3.3347 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8007    0.3407    1.4129 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5341   -0.0242    0.1319 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3327    0.1658   -0.6373 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5147   -0.7851    3.3155 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6034   -2.2083    2.5636 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2014   -1.7267    1.9549 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1880    1.7704    1.0852 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5478    2.3573    1.0816 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9510    3.0166   -1.4134 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9335    3.7912   -0.1159 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3664    3.0070   -1.9592 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7286    2.2337   -0.3698 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3269    0.6026   -2.5528 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9174   -1.9114   -0.8353 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5482   -1.5042   -2.5507 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0643   -2.7847   -1.9190 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5764   -1.6122   -3.1466 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3422   -0.1730   -2.6091 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1189   -1.7957   -2.2868 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5790   -1.4612   -0.4927 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9599   -1.2991    1.4414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5864    0.9346    3.8788 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0554    0.8430    1.9670 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5153    0.8183   -1.4965 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  5  3  1  1
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 22  2  0
 22 21  1  0
 21 19  2  0
 19 20  1  0
 19 17  1  0
 17 18  1  0
 17 16  2  0
 22 23  1  0
 10  5  1  0
 23 12  1  0
 23  5  1  0
 16 15  1  0
  1 24  1  0
  1 25  1  0
  1 26  1  0
  6 27  1  0
  6 28  1  0
  7 29  1  0
  7 30  1  0
  8 31  1  0
  8 32  1  0
  9 33  1  0
 11 34  1  0
 11 35  1  0
 13 36  1  0
 13 37  1  0
 14 38  1  0
 14 39  1  0
 21 43  1  0
 20 42  1  0
 18 41  1  0
 16 40  1  0
 23 44  1  6
M  END


  Mrv1652304282214552D          

 23 26  0  0  1  0            999 V2000
    3.9995   -0.3846    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5835    0.1981    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3708    0.9952    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5742    1.2096    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9902    0.6269    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2029   -0.1702    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2555    1.0022    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.3854    1.8169    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.2004    1.9451    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7448    2.3368    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9743    2.0419    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8444    1.2272    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4850    0.7073    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3551   -0.1074    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5846   -0.4022    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0560    0.1177    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0739    0.9324    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8266   -0.1772    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4546   -1.2169    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3485    0.1084    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6561   -0.3402    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4767   -0.7066    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8350   -1.2251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  1  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  6  0  0  0
  8  9  1  0  0  0  0
  4  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
  7 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 12 17  1  0  0  0  0
 16 18  1  0  0  0  0
 15 19  1  0  0  0  0
  5 20  1  6  0  0  0
 20 21  2  0  0  0  0
 20 22  1  0  0  0  0
 22 23  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0068031

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)[C@@]12CCCC=C1CN1CCC3=C(C=C(O)C(O)=C3)[C@@H]21

> <INCHI_IDENTIFIER>
InChI=1S/C18H21NO4/c1-23-17(22)18-6-3-2-4-12(18)10-19-7-5-11-8-14(20)15(21)9-13(11)16(18)19/h4,8-9,16,20-21H,2-3,5-7,10H2,1H3/t16-,18-/m0/s1

> <INCHI_KEY>
PTTQYTIQSNAMLU-WMZOPIPTSA-N

> <FORMULA>
C18H21NO4

> <MOLECULAR_WEIGHT>
315.369

> <EXACT_MASS>
315.14705816

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
44

> <JCHEM_AVERAGE_POLARIZABILITY>
33.2965126357975

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12-tetraene-17-carboxylate

> <ALOGPS_LOGP>
2.16

> <JCHEM_LOGP>
2.121254382859405

> <ALOGPS_LOGS>
-2.68

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA>
12.820699913602542

> <JCHEM_PKA_STRONGEST_ACIDIC>
9.455782533590689

> <JCHEM_PKA_STRONGEST_BASIC>
8.259944290204144

> <JCHEM_POLAR_SURFACE_AREA>
70.0

> <JCHEM_REFRACTIVITY>
87.0837

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
6.59e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12-tetraene-17-carboxylate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0       7.466  -0.718   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       8.556   0.370   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       8.159   1.858   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       6.672   2.258   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       5.582   1.170   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       5.979  -0.318   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.210   1.871   0.000  0.00  0.00           C+0
HETATM    8  N   UNK     0       4.453   3.392   0.000  0.00  0.00           N+0
HETATM    9  C   UNK     0       5.974   3.631   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       3.257   4.362   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       1.819   3.812   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.576   2.291   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       2.772   1.320   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.529  -0.200   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.091  -0.751   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -0.105   0.220   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       0.138   1.740   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0      -1.543  -0.331   0.000  0.00  0.00           O+0
HETATM   19  O   UNK     0       0.849  -2.272   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       4.384   0.202   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       3.091  -0.635   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0       4.623  -1.319   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0       3.425  -2.287   0.000  0.00  0.00           C+0
CONECT    1    2    6                                                       
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5    9                                                  
CONECT    5    4    6    7   20                                             
CONECT    6    5    1                                                       
CONECT    7    5    8   13                                                  
CONECT    8    7    9   10                                                  
CONECT    9    8    4                                                       
CONECT   10    8   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   17                                                  
CONECT   13   12    7   14                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16   19                                                  
CONECT   16   15   17   18                                                  
CONECT   17   16   12                                                       
CONECT   18   16                                                            
CONECT   19   15                                                            
CONECT   20    5   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20   23                                                       
CONECT   23   22                                                            
MASTER        0    0    0    0    0    0    0    0   23    0   52    0
END

View in JSmol

Synonyms

Value	Source
Methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0,.0,]heptadeca-2,4,6,12-tetraene-17-carboxylic acid	Generator

Chemical Formula

C₁₈H₂₁NO₄

Average Mass

315.3690 Da

Monoisotopic Mass

315.14706 Da

IUPAC Name

methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12-tetraene-17-carboxylate

Traditional Name

methyl (1S,17S)-4,5-dihydroxy-10-azatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12-tetraene-17-carboxylate

CAS Registry Number

Not Available

SMILES

COC(=O)[C@@]12CCCC=C1CN1CCC3=C(C=C(O)C(O)=C3)[C@@H]21

InChI Identifier

InChI=1S/C18H21NO4/c1-23-17(22)18-6-3-2-4-12(18)10-19-7-5-11-8-14(20)15(21)9-13(11)16(18)19/h4,8-9,16,20-21H,2-3,5-7,10H2,1H3/t16-,18-/m0/s1

InChI Key

PTTQYTIQSNAMLU-WMZOPIPTSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Cocculus hirsutus	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as tetrahydroisoquinolines. These are tetrahydrogenated isoquinoline derivatives.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Tetrahydroisoquinolines

Sub Class

Not Available

Direct Parent

Tetrahydroisoquinolines

Alternative Parents

Substituents

Tetrahydroisoquinoline
Isoindole or derivatives
Isoindole
Isoindoline
Pyrrolidine carboxylic acid or derivatives
Pyrrolidine carboxylic acid
1-hydroxy-2-unsubstituted benzenoid
Aralkylamine
Benzenoid
N-alkylpyrrolidine
Methyl ester
Pyrrolidine
Tertiary aliphatic amine
Tertiary amine
Carboxylic acid ester
Amino acid or derivatives
Azacycle
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Carbonyl group
Amine
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.16	ALOGPS
logP	2.12	ChemAxon
logS	-2.7	ALOGPS
pKa (Strongest Acidic)	9.46	ChemAxon
pKa (Strongest Basic)	8.26	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	70 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	87.08 m³·mol⁻¹	ChemAxon
Polarizability	33.3 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

154709417

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Ridge KM, Eriksson JE, Pekny M, Goldman RD: Roles of vimentin in health and disease. Genes Dev. 2022 Apr 1;36(7-8):391-407. doi: 10.1101/gad.349358.122. [PubMed:35487686 ]
Comabella M, Sastre-Garriga J, Carbonell-Mirabent P, Fissolo N, Tur C, Malhotra S, Pareto D, Aymerich FX, Rio J, Rovira A, Tintore M, Montalban X: Serum neurofilament light chain levels predict long-term disability progression in patients with progressive multiple sclerosis. J Neurol Neurosurg Psychiatry. 2022 Apr 29. pii: jnnp-2022-329020. doi: 10.1136/jnnp-2022-329020. [PubMed:35487685 ]
Wezenbeek E, Denolf S, Willems TM, Pieters D, Bourgois JG, Philippaerts RM, De Winne B, Wieme M, Van Hecke R, Markey L, Schuermans J, Witvrouw E, Verstockt S: Association between SARS-COV-2 infection and muscle strain injury occurrence in elite male football players: a prospective study of 29 weeks including three teams from the Belgian professional football league. Br J Sports Med. 2022 Apr 29. pii: bjsports-2021-104595. doi: 10.1136/bjsports-2021-104595. [PubMed:35487684 ]
Wagner JL, Smith KJ, Johnson C, Hilaire ML, Medina MS: Best Practices in Syllabus Design. Am J Pharm Educ. 2022 Apr 29:8995. doi: 10.5688/ajpe8995. [PubMed:35487683 ]
Ahlvik-Harju C: Finding more constructive ways forward in the debate over vaccines with increased disability cultural competence. Med Humanit. 2022 Apr 29. pii: medhum-2021-012342. doi: 10.1136/medhum-2021-012342. [PubMed:35487682 ]

Showing NP-Card for (+)-Haiderine (NP0068031)

MOL for NP0068031 ((+)-Haiderine)

3D MOL for NP0068031 ((+)-Haiderine)

3D SDF for NP0068031 ((+)-Haiderine)

3D-SDF for NP0068031 ((+)-Haiderine)

PDB for NP0068031 ((+)-Haiderine)

3D PDB for NP0068031 ((+)-Haiderine)

SMILES for NP0068031 ((+)-Haiderine)

INCHI for NP0068031 ((+)-Haiderine)

Structure for NP0068031 ((+)-Haiderine)

3D Structure for NP0068031 ((+)-Haiderine)